October 16, 2025

EPA to Prioritize Chemicals Used for Data Centers

EPA will prioritize review of submissions of new chemicals intended for use in data center projects or the manufacturing of related components, according to an agency news release. The agency cited a recent executive order by President Trump that calls for expedited permitting of projects like AI data centers and their infrastructure such as high voltage transmission lines. “In line with this directive, EPA will prioritize review of certain new chemicals to reduce the regulatory burden to companies looking to invest in them,” the news release states.

Manufacturers initiate EPA review of new chemicals by submitting pre-manufacturing notices to the agency. An EPA webpage describes the data needed for submission of PMNs, including the chemical’s identity, structure, and formula; a diagram and description of the process; production volume; byproducts; intended use; and other information.

For more information, refer to the EPA news release.

Related: An article in the March 2025 Synergist discusses the environmental, health, and safety considerations in protecting workers in data centers.